منابع مشابه
Proteomics: The Nucleolus Weighs In
Numerous studies have indicated that the nucleolus is involved in a variety of cellular processes besides its well-known function in ribosome biosynthesis. A recent study describing the nucleolar proteome opens the way to new avenues of research on this important nuclear suborganelle.
متن کاملProteomics Analysis of the Nucleolus in Adenovirus-infected Cells□S
Adenoviruses replicate primarily in the host cell nucleus, and it is well established that adenovirus infection affects the structure and function of host cell nucleoli in addition to coding for a number of nucleolar targeted viral proteins. Here we used unbiased proteomics methods, including high throughput mass spectrometry coupled with stable isotope labeling by amino acids in cell culture (...
متن کاملBone Weighs in on Obesity
Obesity, insulin resistance, and diabetes are related disorders of energy metabolism for which therapies are suboptimal. In this issue of Cell, Lee et al. (2007) demonstrate in mice that bone regulates the insulin/glucose axis and energy metabolism, providing a new framework for approaching common disorders of bioenergetics.
متن کاملThe skate weighs in on kidney regeneration.
Research into kidney organogenesis has seen dramatic growth in recent years, fueled not only by new data on epithelial cell differentiation and the function of genes expressed in the kidney but also by a renewed interest in stem cell biology and its potential application to treating disease. Since the pioneering work of Grobstein in the middle 1950s (1), it has been known that the formation of ...
متن کاملSympathetic tone in the young: the mother weighs in.
The increasingly recognized notion that conditions during fetal life alter susceptibility to adult disease represents a prototype of how the environment can influence biological processes. Several conditions, including stress exposure, maternal nutrition, and environmental temperature, have been shown to affect the health of offspring. The fast-growing epidemic of obesity has witnessed mounting...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2002
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(01)00645-5